Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ic50 for monomerid = 149737
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50:  4.57E+3nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50:  4.57E+3nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50:  4.80E+3nMT: 2°CAssay Description:Test Example 3: The potency of compounds against BACE1 activity was determined in a cellular assay of Aβ production. Human SK-N-BE(2) neuroblas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50:  9.54E+3nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50:  9.54E+3nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50: >1.00E+4nMAssay Description:Test Example 5: The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were perfor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149737(US8975415, RP16a | US8975415, RP16b | US9242973, R...)
Affinity DataIC50: >1.00E+4nMAssay Description:Test Example 5: The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were perfor...More data for this Ligand-Target Pair
In DepthDetails US Patent