Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ic50 for monomerid = 164883
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using cdk7tide peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50: <5nMAssay Description:ETA receptor antagonist activity was measured by inhibition of ET-1 induced vasoconstriction in isolated porcine coronary arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant full length human N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged CyclinT1 (1 to 726 residues) expressed in baculo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  94nMAssay Description:Inhibition of recombinant human His/GST-tagged CDK5/p35 expressed in baculovirus infected Sf9 insect cells using Rb-CTF as substrate after 80 mins in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  94nMAssay Description:Inhibition of recombinant human His/GST-tagged CDK2/Cyclin A expressed in baculovirus infected Sf9 cells using Histone H1 as substrate after 80 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  94nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  94nMAssay Description:Inhibition of recombinant human CDK3/cyclin E expressed in baculovirus infected Sf9 insect cells after 80 mins in presence of [33P]ATP by microbeta s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  94nMAssay Description:Inhibition of recombinant human CDK1/cyclin B expressed in baculovirus infected Sf9 insect cells after 80 mins in presence of [33P]ATP by microbeta s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  96nMAssay Description:Effective concentration required for inhibitory activity towards human beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  130nMAssay Description:Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA Polymerase 2 CTD phosphorylation at Ser2 residues measured after 6 hrs by immunof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  160nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  168nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  219nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  903nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  1.08E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50: >5.00E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50: >5.00E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50: >5.00E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent