Found 11 of ec50 for monomerid = 19441 
Affinity DataKi: 0.370nM ΔG°: -12.7kcal/mole EC50: 4.32nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 2.74nM ΔG°: -11.6kcal/mole EC50: 4.32nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataIC50: 22nM EC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 22nM EC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 260nM EC50: 341nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 260nM EC50: 341nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMT: 2°CAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMT: 2°CAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Activity against estrogen receptor alphaMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
City Of Hope National Medical Center
Curated by ChEMBL
City Of Hope National Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.17E+4nMAssay Description:Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 0.660nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
