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Found 3 of ec50 for monomerid = 20321
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

LigandPNGBDBM20321(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Affinity DataKi:  53.5nM ΔG°:  -10.3kcal/mole EC50:  9.20nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

LigandPNGBDBM20321(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20321(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Affinity DataEC50:  8nMAssay Description:Concentration required to antagonized capsaicin-induced calcium uptake at the transient receptor potential cation channel (subfamily V member 1) expr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed