Found 7 of ec50 for monomerid = 222178 TargetReverse transcriptase(Human immunodeficiency virus 1)
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 3.60nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Inhibition of HIV RT K103N/Y181C mutant by cell based assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetReverse transcriptase(Human immunodeficiency virus 1)
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Inhibition of HIV-1 reverse transcriptase Y188L mutant assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Inhibition of HIV-1 reverse transcriptase E138K mutant assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 1.30nMAssay Description:Inhibition of HIV-1 reverse transcriptase Y181C mutant assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Inhibition of HIV-1 reverse transcriptase K103N mutant assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
