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Found 16 of ic50 for monomerid = 236643
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50:  3.70E+3nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 4 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A1)(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE2A1 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A1)(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE2A1 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A1)(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 4 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A1)(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >5.00E+4nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >1.00E+5nMAssay Description:The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236643(US9388139, 12)
Affinity DataIC50: >1.00E+5nMAssay Description:The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent