Affinity DataIC50: 140nMAssay Description:Inhibition of human Eg5 catalytic domain assessed as inhibition of microtubulin-induced ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of basal ATPase activity of Eg5 by coupled pyruvate kinase/lactate dehydrogenase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 285nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 352nMAssay Description:Inhibition of microtubule-stimulated ATPase activity of N-terminal His-6-tagged human wild type Eg5 (1 to 368) expressed in Escherichia coli BL21 by ...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mitotic kinesin Eg5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Eg5 catalytic domain basal ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ...More data for this Ligand-Target Pair