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Found 10 of ic50 for monomerid = 23772
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human Eg5 catalytic domain assessed as inhibition of microtubulin-induced ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  186nMAssay Description:Inhibition of basal ATPase activity of Eg5 by coupled pyruvate kinase/lactate dehydrogenase assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  285nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  352nMAssay Description:Inhibition of microtubule-stimulated ATPase activity of N-terminal His-6-tagged human wild type Eg5 (1 to 368) expressed in Escherichia coli BL21 by ...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of mitotic kinesin Eg5 (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human Eg5 catalytic domain basal ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  1.90E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11 [1-973](Homo sapiens (Human))
University of Santiago De Compostela

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  1.95E+3nMAssay Description:The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ...More data for this Ligand-Target Pair