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Found 6 of ic50 for monomerid = 27504
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  5.89E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  9.50E+3nMAssay Description:The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  2.57E+4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  3.45E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed