TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute
Human Biomolecular Research Institute
Affinity DataKi: 1.10nM ΔG°: -12.1kcal/mole EC50: 7.30nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute
Human Biomolecular Research Institute
Affinity DataKi: 1.56E+3nM EC50: 1.02E+3nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute
Human Biomolecular Research Institute
Affinity DataKi: 6.67E+3nM ΔG°: -6.99kcal/mole EC50: 1.95E+4nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute
Human Biomolecular Research Institute
Affinity DataEC50: 2.70nMAssay Description:Inhibition of human SERT-mediated serotonin reuptake in HEK293 cellsMore data for this Ligand-Target Pair