TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Inhibition of human recombinant IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after 10 mins by...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli assessed as reduction in formation of N-formylkynurenine by measuring apparent inh...More data for this Ligand-Target Pair
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology
Curated by ChEMBL
Wroc?Aw University Of Technology
Curated by ChEMBL
Affinity DataKi: 226nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 300nM IC50: 6.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one
derivatives were tested as potential E. coli TrxR inhibitors by standard
DTNB ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne
Ecole Polytechnique FÉDÉRale De Lausanne
Affinity DataKi: 570nM IC50: 2.40E+3nMpH: 6.5Assay Description:The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne
Ecole Polytechnique FÉDÉRale De Lausanne
Affinity DataKi: 570nMAssay Description:Inhibition of recombinant human MIF tautomerization expressed in Escherichia coli BL21/DE3 using HPP as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 9.40E+4nMAssay Description:Binding affinity to human recombinant IDO1 assessed as inhibition constant using L-tryptophan as substrate incubated for 10 mins by methylene blue dy...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair