Affinity DataIC50: 2.60nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human NQO1 assessed as reduction in oxidation of NADPH to NADP+ using b-lap as substrate and NADPH in presence of 0.14% (w/...More data for this Ligand-Target Pair
Affinity DataIC50: 404nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO1 in presence of BSAMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 7(Homo sapiens (Human))
Universidade Estadual Paulista
Curated by ChEMBL
Universidade Estadual Paulista
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of jack bean ureaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Francisella tularensis subsp. tularensis (strain S...)
Naval Research Laboratories
Curated by ChEMBL
Naval Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of C-terminal His6-tagged Francisella tularensis SCHU S4 FabI expressed in Escherichia coli BL21 (DE3) using CrCoA as substrate assessed a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against 3'-processing of DNA by HIV-1 integraseMore data for this Ligand-Target Pair