Compile Data Set for Download or QSAR
maximum 50k data
Found 13 of ic50 for monomerid = 50004233
TargetCytochrome P450 1A1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  19nMAssay Description:Bioactivation in CYP1A1 (unknown origin) transfected CHO cells assessed as CYP1A1-mediated drug activation by measuring reduction in cell viabilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of topoisomerase 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50: >3.67E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  4.09E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  6.68E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  1.67E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of p56lck autophosphorylationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiphosphomevalonate decarboxylase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  1.19E+5nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50: <6.08E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed