Affinity DataIC50: 2.10E+3nMAssay Description:Reversible inhibition of human MAO-BMore data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(Homo sapiens)
California Institute Of Technology
Curated by ChEMBL
California Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.19E+3nMAssay Description:Inhibition of SDH-A (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
California Institute Of Technology
Curated by ChEMBL
California Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.19E+3nMAssay Description:Inhibition of COX1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of CALML3 (unknown origin) assessed as apparent protein translation inhibition constant incubated for 5 hrs by SDS gel electrophoresisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Micurx Pharmaceuticals
Curated by ChEMBL
Micurx Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in yeast after 1 hr by luciferin-based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was evaluated for inhibition of Mono aminoxidase B in rat primary hepatocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Research Foundation Itsuu Laboratory
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Micurx Pharmaceuticals
Curated by ChEMBL
Micurx Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of MAO-A (unknown origin) using tyramine as substrate after 30 to 60 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of Escherichia coli DNA gyrase using fluorescence-tagged DNA by fluorescenct polarization assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Micurx Pharmaceuticals
Curated by ChEMBL
Micurx Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Reversible inhibition of human MAO-AMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Chantest
Curated by ChEMBL
Chantest
Curated by ChEMBL
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair