Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ic50 for monomerid = 50184807
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant VEGFR-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant FGFR-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant FGFR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity against Flk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  148nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  380nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >1.90E+3nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory activity against LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against hERG by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyl-trifluoromethyl coumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against PKC alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxyresorufinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed