Found 48 of ec50 for monomerid = 84637 
Affinity DataEC50: 19nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at human Dopamine D2S receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 min...More data for this Ligand-Target Pair
Affinity DataEC50: 8.70nMAssay Description:Effective concentration to stimulate human Dopamine receptor D4.2 mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 17nMAssay Description:Effective concentration to stimulate rat Dopamine receptor D2S mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Effective concentration to stimulate human Dopamine receptor D3 mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Intrinsic activity against dopamine D2(long) receptor expressed in CHO cells by GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Intrinsic activity against dopamine D3 receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40nMAssay Description:Intrinsic activity against dopamine D2(long) receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Intrinsic activity against dopamine D2(short) receptor expressed in CHO cells by GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Intrinsic activity against dopamine D4 receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Intrinsic activity against dopamine D2(short) receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Intrinsic activity against dopamine D4 receptor expressed in CHO cells by GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as rate of [3H]thymidine incorporation by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO dhfr mutant cells assessed as stimulation of mitogenesis after 4 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporationMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at DRD2 Long receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation by bioluminescence ass...More data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Effective concentration of compound required against human Dopamine D4.2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Tested for the effective concentration against CHO 10001 cells in human D4.2 receptor established in mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.60nMAssay Description:In vitro inhibition of forskolin-stimulated cAMP accumulation in GH4C1 cells transfected with the human Dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70nMAssay Description:Effective dose was measured by the stimulation of mitogenesis at Dopamine receptor D4.2More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 2.20nMAssay Description:Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D2L from ratMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Centre For Pharmacy
Curated by ChEMBL
University Centre For Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D3 from ratMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay (intri...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay (intrin...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10nMAssay Description:Intrinsic activity in mitogenesis assay using Dopamine receptor D3 expressing CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Centre For Pharmacy
Curated by ChEMBL
University Centre For Pharmacy
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Basal binding towards Dopamine receptor D3 was evaluated using [35S]- GTP-gamma S radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Effective concentration from [3H]thymidine uptake assay in CHO10001 cells expressing human Dopamine receptor D4.2More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Effective concentration in [3H]thymidine uptake assay by CHO dhfr- mutant cells expressing human D3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding in CHO-K1 cells expressing human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Effective concentration against dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Activity at human D4.2 receptor assessed as [3H]thymidine incorporation in CHO 10001 cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Activity at human D4.4 receptor expressed in CHOK1 cells assessed as stimulation of [35S]GTP-gammaS bindingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 9.90nMAssay Description:Effective concentration for [3H]thymidine uptake in growing CHO cells stably expressing the dopamine D4.2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells by by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.40nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...More data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoA ...More data for this Ligand-Target Pair
Affinity DataEC50: 64nMAssay Description:Agonist activity at ARMS2-PK2 tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of EA-tagged beta-arrestin-2 recru...More data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
Affinity DataEC50: 295nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
Affinity DataEC50: 5.90nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai3 ...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai2 ...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 48nMAssay Description:Effective concentration to stimulate rat Dopamine receptor D2L mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
