Affinity DataKd: 0.0460nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0530nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 0.0530nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.70nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.30nMAssay Description:Binding affinity to recombinant GSK3B (unknown origin) assessed as dissociation constant by DSF assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.30nMAssay Description:Binding affinity to human full length GSK-3 beta (M1 to T433 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.20nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.70nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.30nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m...More data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to human C-terminal his tagged GSK3beta (26 to 383 residues) expressed in Escherichia coli at 50 uM by radiometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 38nMAssay Description:Binding affinity to human C-terminal his tagged GSK3beta (26 to 383 residues) expressed in Escherichia coli at 12.5 uM by radiometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 126nMAssay Description:Binding affinity to GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 148nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged GSK3B (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
Affinity DataKd: 155nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 214nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged GSK3B (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 260nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 396nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataKd: 475nMAssay Description:Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair