Compile Data Set for Download or QSAR
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Found 198 of ic50 for UniProtKB: Q8NI77
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535532(N-(2-(4,4-Difluoropiperidin-1-yl)-6- methylpyrimid...)
Affinity DataIC50:  17nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50561924(CHEMBL4750775 | US11236069, Example 6-29)
Affinity DataIC50:  17nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50561923(CHEMBL4751673 | US11236069, Example 6-24-1)
Affinity DataIC50:  17.4nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50561926(CHEMBL4776120 | US11236069, Example 11-25)
Affinity DataIC50:  17.6nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50561927(CHEMBL4740783 | US11236069, Example 11-62)
Affinity DataIC50:  18nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50561925(CHEMBL4743241 | US11236069, Example 11-4)
Affinity DataIC50:  18nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535665((R)-N-(2-(3,3-Difluoroazetidin- 1-yl)-6-methylpyri...)
Affinity DataIC50:  20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535618(N-(2-((1R,5S)-3- Azabicyclo[3.1.0]hexan-3-yl)- 6-m...)
Affinity DataIC50:  20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535616((R)-N-(2-(3-Fluoro-3- methylpyrrolidin-1-yl)-6- me...)
Affinity DataIC50:  20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535640(N-(2-(4-Fluoropiperidin-1-yl)- 6-methylpyrimidin-4...)
Affinity DataIC50:  20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535564((R)-N-(2-(4,4- Difluoropiperidin-1- yl)pyrimidin-4...)
Affinity DataIC50:  21nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535652(N-(2-(4,4-Difluoropiperidin-1- yl)-3-fluoropyridin...)
Affinity DataIC50:  22nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535646(N-(2-(4,4-Difluoropiperidin-1- yl)pyrimidin-4-yl)-...)
Affinity DataIC50:  22nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535645(N-(2-(4-Fluoropiperidin-1- yl)pyrimidin-4-yl)-4-((...)
Affinity DataIC50:  22nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535597(N-(2-(3,3-Difluoroazetidin-1- yl)pyrimidin-4-yl)-4...)
Affinity DataIC50:  23nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535689(N-(2-(4,4-Difluoropiperidin-1- yl)pyridin-4-yl)-4-...)
Affinity DataIC50:  23nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535693(N-(2-(4,4-Difluoropiperidin-1- yl)pyrimidin-4-yl)-...)
Affinity DataIC50:  23nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535584(N-(2-(3,3-Difluoroazetidin-1-yl)-6- methylpyrimidi...)
Affinity DataIC50:  23nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535690(4-(N-(2- Hydroxyethyl)sulfamoyl)-2-(6- azaspiro[2....)
Affinity DataIC50:  27nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535592(4-((2-Hydroxyethyl)sulfonamido)-N- (2-isopropyl-6-...)
Affinity DataIC50:  27nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535560(4-(((R)-2-hydroxy-1- methylethyl)sulfonamido)-N- (...)
Affinity DataIC50:  28nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535526(N-(2-(4,4-Difluoropiperidin-1- yl)pyridin-4-yl)-4-...)
Affinity DataIC50:  29nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535563((S)-N-(2-(4,4- Difluoropiperidin-1- yl)pyrimidin-4...)
Affinity DataIC50:  31nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535595(N-(2-(3-Fluoroazetidin-1-yl)-6- methylpyrimidin-4-...)
Affinity DataIC50:  32nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535551(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  32nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535520(N-(6-Methyl-2-(3,3,3- trifluoropropoxy)pyrimidin-4...)
Affinity DataIC50:  32nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535538((R)-4-((2- Hydroxyethyl)sulfonamido)- N-(2-(2- met...)
Affinity DataIC50:  32nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535619(N-(2-(3,3-Difluoropyrrolidin-1- yl)-6-methylpyrim-...)
Affinity DataIC50:  33nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535633(N-(2-((1S,6R)-2- Azabicyclo[4.1.0]heptan-2-yl)- 6-...)
Affinity DataIC50:  33nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535656(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  34nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535631(N-(2-((1R)-1-Hydroxy-3- azabicyclo[4.1.0]heptan-3-...)
Affinity DataIC50:  34nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535666((S)-N-(2-(3,3-Difluoroazetidin- 1-yl)-6-methylpyri...)
Affinity DataIC50:  34nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535703(2-(6-Azaspiro[2.5]octan-6- yl)-N-(2-(4,4-difluoro-...)
Affinity DataIC50:  35nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535634((S)-4-((2- Hydroxyethyl)sulfonamido)-N- (6-methyl-...)
Affinity DataIC50:  35nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535632(N-(2-((1R,6R)-3- Azabicyclo[4.1.0]heptan-3-yl)- 6-...)
Affinity DataIC50:  35nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535591((S)-4-((2-Hydroxyethyl)sulfonamido)-N- (2-(2-methy...)
Affinity DataIC50:  37nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535558(4-(((R)-2-Hydroxy-1- methylethyl)sulfonamido)-N- (...)
Affinity DataIC50:  37.3nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535570(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyridin...)
Affinity DataIC50:  38.4nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535557(4-(((S)-2-Hydroxy-1- methylethyl)sulfonamido)-N- (...)
Affinity DataIC50:  39nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535555(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  39nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535553(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  39nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535546(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  40nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535710(4-(Azetidin-3-ylsulfonyl)-N-(2-(4,4- difluoropiper...)
Affinity DataIC50:  40nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535644((R)-N-(2-(3-Fluoro-3- methylpiperidin-1-yl)-6- met...)
Affinity DataIC50:  41nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535562((R)-N-(2-(4-Fluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  41nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535705(4-(Cyclopropanesulfonimidoyl)- N-(2-(4,4-difluorop...)
Affinity DataIC50:  42nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535691(4-(N-(2- Hydroxyethyl)sulfamoyl)-N-(6- methyl-2-(3...)
Affinity DataIC50:  42nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535660((R)-N-(2-(3,3-Difluoroazetidin- 1-yl)-6-methylpyri...)
Affinity DataIC50:  42nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535536(N-(2-(4,4-Difluoropiperidin-1- yl)-6-methylpyrimid...)
Affinity DataIC50:  42nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A [1-467](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM535624((S)-N-(2-(3-Cyanopiperidin-1- yl)-6-methylpyrimidi...)
Affinity DataIC50:  43nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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