Affinity DataKd: 0.195nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to human STING (137 to 379 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 0.440nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 0.780nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding affinity to human STING assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKd: 1.5nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 1.58nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding affinity to human C-terminal domain STING (139 to 379 residues) assessed as dissociation constant by scanning fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding affinity to human wild type STING assessed as dissociation constantMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataKd: 1.70nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataKd: 1.70nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to wild type human STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.79nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) expressed in E. coli assessed as dissociation constant by isothermal titratio...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to human STING assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKd: 4nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 4.85nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataKd: 6nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 6.20nMAssay Description:Binding affinity to wild type human STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 9nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataKd: <10nMAssay Description:Compounds were analyzed on an S200 biacore SPR instrument (GE Healthcare). E. coli produced truncated STING protein was immobilized on a series S str...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
