TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TACE (unknown origin) using fluorogenic LAQAVRSSSR peptide as a substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.398nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C gamma C1b domainMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TACE (unknown origin) using fluorogenic LAQAVRSSSR peptide as a substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.420nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:In vitro displacement of [3H]- SCH 23390 from the dopamine receptor D1 of bovine striatal membraneMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.530nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporterMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Compound was tested for its ability to inhibit high-affinity uptake of [3H]NE into parietal and occipital cortex in ratMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair