Compile Data Set for Download or QSAR
maximum 50k data
Found 91 of ec50 for UniProtKB: P55210
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataEC50:  2.20nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273991((S)-1-(4-Fluorobenzyl)-5-(2-(pyrimidin-4-yloxymeth...)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273927((S)-1-(4-Fluorobenzyl)-5-(2-(4-fluorophenoxymethyl...)
Affinity DataEC50:  8nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273929((S)-1-(4-Fluorobenzyl)-5-(2-(2,4-difluorophenoxyme...)
Affinity DataEC50:  13nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273928((S)-1-(4-Fluorobenzyl)-5-(2-(3-fluorophenoxymethyl...)
Affinity DataEC50:  13.5nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273990((S)-1-(4-Fluorobenzyl)-5-(2-(tetrahydro-2H-pyran-4...)
Affinity DataEC50:  14.4nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50462076(CHEMBL1091826)
Affinity DataEC50:  16nMAssay Description:Activation of caspase cascade in human T47D cells using N-(Ac-DEVD)-N'-ethoxycarbonyl-R110 fluorogenic substrate incubated for 48 hrs by fluorescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273989((S)-1-(4-Fluorobenzyl)-5-(2-(3,5-difluorophenoxyme...)
Affinity DataEC50:  16.8nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588263(CHEMBL5198038)
Affinity DataEC50:  17nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273339((S)-1-(4-Fluorobenzyl)-5-(2-((1-(2-fluoroethyl)-1H...)
Affinity DataEC50:  18.3nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM10331((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...)
Affinity DataEC50:  19.8nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588262(CHEMBL5197170)
Affinity DataEC50:  21nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588264(CHEMBL5207871)
Affinity DataEC50:  21nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588284(CHEMBL5204473)
Affinity DataEC50:  24nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50200305((S)-1-(4-iodobenzyl)-5-(2-phenoxymethyl-pyrrolidin...)
Affinity DataEC50:  25.3nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataEC50:  28.2nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM167534(US9073922, 18 | US9796708, Example 18)
Affinity DataEC50:  29nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM10323((S)-1-Benzyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)
Affinity DataEC50:  29.4nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588290(CHEMBL5191725)
Affinity DataEC50:  31nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588272(CHEMBL5180640)
Affinity DataEC50:  41nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588266(CHEMBL5181709)
Affinity DataEC50:  57nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273992((S)-1-(2-Propynyl)-5-(2-(2,4-difluorophenoxymethyl...)
Affinity DataEC50:  60.4nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588279(CHEMBL5198372)
Affinity DataEC50:  66nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588287(CHEMBL5192022)
Affinity DataEC50:  69nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM167545(US9073922, 29 | US9796708, Example 29)
Affinity DataEC50:  75nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588286(CHEMBL5177440)
Affinity DataEC50:  76nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50273926(1-(4-Fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isati...)
Affinity DataEC50:  78.6nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588274(CHEMBL5195947)
Affinity DataEC50:  120nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588285(CHEMBL5179773)
Affinity DataEC50:  130nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588283(CHEMBL5169733)
Affinity DataEC50:  130nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588289(CHEMBL5181511)
Affinity DataEC50:  140nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588255(CHEMBL5170195)
Affinity DataEC50:  140nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588273(CHEMBL5192311)
Affinity DataEC50:  290nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588288(CHEMBL5200778)
Affinity DataEC50:  290nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588277(CHEMBL5203694)
Affinity DataEC50:  340nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588261(CHEMBL5170524)
Affinity DataEC50:  350nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588276(CHEMBL5176464)
Affinity DataEC50:  420nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588270(CHEMBL5173492)
Affinity DataEC50:  430nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588267(CHEMBL5209369)
Affinity DataEC50:  450nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588278(CHEMBL5171361)
Affinity DataEC50:  450nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588271(CHEMBL5207146)
Affinity DataEC50:  510nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588269(CHEMBL5199352)
Affinity DataEC50:  750nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588268(CHEMBL5187219)
Affinity DataEC50:  1.50E+3nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588265(CHEMBL5207813)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588280(CHEMBL5192909)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588258(CHEMBL5173041)
Affinity DataEC50:  2.70E+3nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM77503(MLS000697060 | N-(3-allyl-6-sulfamoyl-1,3-benzothi...)
Affinity DataEC50: >3.16E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSR...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM36363(CID6851947 | PAC-1 | US10166229, Example PAC-1)
Affinity DataEC50:  4.50E+3nMpH: 7.4 T: 2°CAssay Description:Procaspase-7 activation assay; activation of procaspase-7 to caspase-7. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3/Caspase-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50588282(CHEMBL5198594)
Affinity DataEC50:  6.90E+3nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCaspase-7(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM77499(2-(2-Methoxy-phenylamino)-8-methyl-quinoline-3-car...)
Affinity DataEC50:  9.49E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSR...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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