Compile Data Set for Download or QSAR
maximum 50k data
Found 139 of ic50 for UniProtKB: P07949
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM576988(US11472802, Example 8)
Affinity DataIC50:  0.0170nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577053(US11472802, Example 58)
Affinity DataIC50:  0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577046(7-chloro-3-(5-cyclopropyl- 4-(1H-pyrazol-3- yl)iso...)
Affinity DataIC50:  0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577049(US11472802, Example 55)
Affinity DataIC50:  0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577063(1-(3-(4-amino-7-chloro-1- isopropyl-1H-pyrazolo[4,...)
Affinity DataIC50:  0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577050(7-chloro-3-(5- cyclopropyl-4-(1H- imidazol-4- yl)i...)
Affinity DataIC50:  0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577026(7-chloro-3-(5-cyclopropyl-4-(4- methylpyridin-2-yl...)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577025(7-chloro-3-(5-cyclopropyl-4- (pyrazin-2-yl)isoxazo...)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM576996(US11472802, Example 11)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577061(US11472802, Example 65)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597662(US11603374, Example 17)
Affinity DataIC50:  0.300nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577066(3-(5-cyclopropyl- 4-(1H-pyrazol-3- yl)isoxazol-3- ...)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577064(US11472802, Example 68)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577045(US11472802, Example 51)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577029(7-chloro-3-(5-cyclopropyl-4-(5- methylpyridin-2-yl...)
Affinity DataIC50:  0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597647(US11603374, Example 2)
Affinity DataIC50:  0.400nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577062(1-(3-(4-amino-7-chloro-1- isopropyl-1H-pyrazolo[4,...)
Affinity DataIC50:  0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597673(US11603374, Example 28)
Affinity DataIC50:  0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577047(7-chloro-3-(5-cyclopropyl- 4-(1-methyl-1H-pyrazol-...)
Affinity DataIC50:  0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597646(US11603374, Example 1)
Affinity DataIC50:  0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577067(3-(5-cyclopropyl- 4-(5-methyl-1H- pyrazol-3-yl) is...)
Affinity DataIC50:  0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597674(US11603374, Example 29)
Affinity DataIC50:  0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597672((3-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-py...)
Affinity DataIC50:  0.600nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577032(US11472802, Example 39)
Affinity DataIC50:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577048(7-chloro-3-(5-cyclopropyl- 4-(1-ethyl-1H-pyrazol-3...)
Affinity DataIC50:  0.700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597675(US11603374, Example 30)
Affinity DataIC50:  0.700nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM576985(US11472802, Example 6)
Affinity DataIC50:  0.700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597663(7-cyclobutyl-5-(5- cyclopropylisoxazol-3-yl)- 7H-p...)
Affinity DataIC50:  0.700nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM625349(US20230322769, Compound 58 | US20230322769, Compou...)
Affinity DataIC50:  0.75nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597648(US11603374, Example 3)
Affinity DataIC50:  0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577022(3-(5-cyclopropyl-4-(1-methyl- 1H-imidazol-4-yl)iso...)
Affinity DataIC50:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577028(7-chloro-3-(5-cyclopropyl-4-(6- methylpyridin-2-yl...)
Affinity DataIC50:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597669(5-(5-cyclopropylisoxazol-3- yl)-7-(1,1,1-trifluoro...)
Affinity DataIC50:  0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577015(3-(5-cyclopropyl-4-(4- methylpyridin-2-yl)isoxazol...)
Affinity DataIC50:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM625352(US20230322769, Compound 65)
Affinity DataIC50:  0.920nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577065(US11472802, Example 69)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597668(2-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-pyr...)
Affinity DataIC50:  1nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577019(3-(5-cyclopropyl-4-(5- methylpyridin-2-yl)isoxazol...)
Affinity DataIC50:  1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577006(US11472802, Example 17)
Affinity DataIC50:  1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597665(US11603374, Example 20)
Affinity DataIC50:  1.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577008(US11472802, Example 19)
Affinity DataIC50:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597676(US11603374, Example 31)
Affinity DataIC50:  1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM597649(US11603374, Example 4)
Affinity DataIC50:  1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM625338(US20230322769, Compound 20)
Affinity DataIC50:  1.45nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM625369(US20230322769, Compound 89)
Affinity DataIC50:  1.47nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM576971(US11472802, Example 1)
Affinity DataIC50:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM625351(US20230322769, Compound 64 | US20230322769, Compou...)
Affinity DataIC50:  1.62nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM625337(US20230322769, Compound 17)
Affinity DataIC50:  1.70nMAssay Description:The activity assay method for the above kinases was established by homogeneous time-resolved fluorescence (HTRF), and the inhibitory activity of the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM577007(US11472802, Example 18)
Affinity DataIC50:  1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [M918T](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM576973(US11472802, Example 3)
Affinity DataIC50:  1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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