Compile Data Set for Download or QSAR
maximum 50k data
Found 94 of ic50 for UniProtKB: O60674
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM608209(US11691971, Example 1)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604321(US11661422, Example 25)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM608213(US11691971, Example 5)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM608216(US11691971, Example 8)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620452(US11767323, Example 2)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620456(US11767323, Example 6)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620458(US11767323, Example 8)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620459(US11767323, Example 9)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620460(US11767323, Example 10)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620461(US11767323, Example 11)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620462(US11767323, Example 12)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620463(US11767323, Example 13)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620464(US11767323, Example 14)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620466(US11767323, Example 16)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620470(US11767323, Example 20)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620471(US11767323, Example 21)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620472(US11767323, Example 22)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620473(US11767323, Example 23)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620474(US11767323, Example 24)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620475(US11767323, Example 25)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620476(US11767323, Example 26)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620477(US11767323, Example 27)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620478(US11767323, Example 28)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620479(US11767323, Example 29)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620480(US11767323, Example 30)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620481(US11767323, Example 31)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620482(US11767323, Example 32)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620483(US11767323, Example 33)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620484(US11767323, Example 34)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620485(US11767323, Example 35)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620486(US11767323, Example 36)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620487(US11767323, Example 37)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620488(US11767323, Example 38)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620489(US11767323, Example 39)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620492(US11767323, Example 42)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620493(US11767323, Example 43)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM620494(US11767323, Example 44)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604258(US11661422, Example 3)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604304(US11661422, Example 10)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604307(US11661422, Example 11)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604308(4-(9-(4-methoxyphenyl)-4-methyl-8-(4-((4-(methylsu...)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604309(US11661422, Example 13)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604310(US11661422, Example 14)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604312(US11661422, Example 16)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604313(4-(2-(tert-Butyl)-4- methyl-8-(4-((4- (methylsulfo...)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604314(9-(4-(4-Acetylpiperazin- 1-yl)phenyl)-2-(tert- but...)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604315(US11661422, Example 19)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604316(US11661422, Example 20)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604317(4-(9-(4-(1- Aminocyclopropyl) phenyl)-4-methyl-8-(...)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 JH2 WT (536-812)(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM604318(4-(4-Methyl-9-(1- methyl-1H-pyrrol-3-yl)- 8-(4-((4...)
Affinity DataIC50: <100nMAssay Description:JAK2 JH2-WT binding assay utilizes pseudo-kinase domain (JH2, amino-acids 536-812 with 3 surface mutations W659A, W777A, F794H) of human Wild Type JA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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