Compile Data Set for Download or QSAR
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Found 16 of affinity data for UniProtKB/TrEMBL: P12882
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645010((S)-6-((1-(2-Fluoro-5-((6-methylpyridin-3-yl)oxy)p...)
Affinity DataIC50:  350nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645002((S)-6-((1-(5-Cyclopropyl-2-fluorophenyl)ethyl)amin...)
Affinity DataIC50:  450nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645006(US20240010639, Example 10)
Affinity DataIC50:  620nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645005((S)-6-((l-(2,3-Dihydro-1H-inden-5-yl)ethyl)amino)-...)
Affinity DataIC50:  680nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645008((S)-6-((1-(2-Fluoro-5-((6-methylpyridin-3-yl)oxy)p...)
Affinity DataIC50:  810nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645009((S)-6-((1-(2-Fluoro-5-methylphenyl)ethyl)amino)-3-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645012((S)-6-((1-(2-Fluoro-5-methylphenyl)ethyl)amino)-3-...)
Affinity DataIC50:  1.06E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645011((S)-6-((1-(3-((6-Methylpyridin-3-yl)oxy)phenyl)eth...)
Affinity DataIC50:  1.13E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645003((S)-6-((1-(Bicyclo[4.2.0]octan-1 | US20240010639, ...)
Affinity DataIC50:  1.33E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645007((S)-6-((1-(5-Fluoro-2,3-dihydrobenzofuran-6-yl)eth...)
Affinity DataIC50:  1.39E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645000((S)-3-Isopropyl-6-((1-(3-((6-methylpyridin-3-yl)ox...)
Affinity DataIC50:  1.66E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645001((S)-3-Isopropyl-6-((1-(3-(trifluoromethoxy)phenyl)...)
Affinity DataIC50:  1.98E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM644997(6-(((S)-1-(2-Fluoro-5-(((S)-tetrahydrofuran-3-yl)o...)
Affinity DataIC50:  2.41E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM644998(6-(((S)-1-(2-Fluoro-5-(((R)-tetrahydrofuran-3-yl)o...)
Affinity DataIC50:  2.55E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645004((S)-6-((1-(2,3-Dihydrobenzofuran-6-yl)ethyl)amino)...)
Affinity DataIC50:  3.75E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM644999(3-Isopropyl-6-(((1S)-1-(3-((tetrahydrofuran-3-yl)o...)
Affinity DataIC50:  5.11E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent