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TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258601BDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 0.0550nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 139540BDBM139540(US8889696, Staurosporine | US9051313, Staurosporin...)
Affinity DataIC50: 0.678nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.935nMAssay Description:Inhibition of human PKA using LCGRTGRRNSI as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.58nMAssay Description:Inhibition of human PKACA using LCGRTGRRNSI as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258598BDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 1.79nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PKACalpha (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258600BDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 3.38nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 3149BDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human PKAC-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773718BDBM773718(D0157 | US20250299772, Compound 16)
Affinity DataIC50: 4nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258595BDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 4.06nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50311410BDBM50311410(N-((5S,8R,11R,14R,17R,20R,23R,33R)-1-amino-33-(4-a...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of PKACalpha in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 2683BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PKAC-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50199310BDBM50199310(2S,3S,4R,5R)-5-6-amino-9H-purin-9-yl)-N-12R,15R,18...)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100 uM ATP and 30 uM TAMRA-kemptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50199310BDBM50199310(2S,3S,4R,5R)-5-6-amino-9H-purin-9-yl)-N-12R,15R,18...)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100 uM ATP and 30 uM TAMRA-kemptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50311409BDBM50311409(N-((6R,9R,12R,15R,18R,21R,31R)-1-amino-31-(4-amino...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PKACalpha in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50599148BDBM50599148(CHEMBL5188777)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of ARC-1063 fluorescent probe binding to recombinant human PKAC-alpha incubated for 1 hr by time-gated luminescence intensity based displa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258596BDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 6.09nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773716BDBM773716(DM009 | US20250299772, Compound 14)
Affinity DataIC50: 7nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258599BDBM258599(US9493490, Example 11 | US9493490, tert-butyl 2-fl...)
Affinity DataIC50: 7.88nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773715BDBM773715(D1011 | US20250299772, Compound 13)
Affinity DataIC50: 8nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 27248BDBM27248(CHEMBL279185 | 6-{[(2S,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataIC50: 8.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100 uM ATP and 30 uM TAMRA-kemptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 27248BDBM27248(CHEMBL279185 | 6-{[(2S,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataIC50: 8.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100 uM ATP and 30 uM TAMRA-kemptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 687757BDBM687757(US20240246972, Compound 4 | Synthesis of N-(1-(2-f...)
Affinity DataIC50: 9.90nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50242733BDBM50242733(AT-13148)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged PKA catalytic domain (1 to 351 residues) expressed in Escherichia coli using Ser/Thr 7 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773714BDBM773714(DM010 | US20250299772, Compound 12)
Affinity DataIC50: 10nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258597BDBM258597(US9493490, Example 9 | US9493490, F)
Affinity DataIC50: 11.0nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50219803BDBM50219803(6-{[(1S,3R,4R)-3-(6-amino-9H-purin-9-yl)-4-hydroxy...)
Affinity DataIC50: 12.9nMAssay Description:Inhibition of cAPK Calpha in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773713BDBM773713(D0101 | US20250299772, Compound 11)
Affinity DataIC50: 13nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773717BDBM773717(D0011 | US20250299772, Compound 15)
Affinity DataIC50: 13nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50311405BDBM50311405(N-((6R,9R,19R)-1-amino-19-(4-aminobutyl)-6-carbamo...)
Affinity DataIC50: 14nMAssay Description:Inhibition of PKACalpha in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773712BDBM773712(D1008 | US20250299772, Compound 10)
Affinity DataIC50: 19nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773711BDBM773711(D0139 | US20250299772, Compound 9)
Affinity DataIC50: 22nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50599147BDBM50599147(CHEMBL5201435)
Affinity DataIC50: 24nMAssay Description:Inhibition of ARC-1063 fluorescent probe binding to recombinant human PKAC-alpha incubated for 1 hr by time-gated luminescence intensity based displa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773710BDBM773710(D0054 | US20250299772, Compound 8)
Affinity DataIC50: 26nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50536679BDBM50536679(CHEMBL4568087)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human His-tagged PRKACA catalytic domain expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 511482BDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50: 29nMAssay Description:Inhibition of various kinases was assayed.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 511482BDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50: 29nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773709BDBM773709(D0069 | US20250299772, Compound 7)
Affinity DataIC50: 30nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 3153BDBM3153(CHEMBL52529 | 2-{[2,6-dihydroxy-4-({[(1R,2R)-2-[(4...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773708BDBM773708(D1010 | US20250299772, Compound 6)
Affinity DataIC50: 31nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773707BDBM773707(D0137 | US20250299772, Compound 5)
Affinity DataIC50: 40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50358480BDBM50358480(CHEMBL1922132 | US20240246972, Comparator 6)
Affinity DataIC50: 46.2nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 258594BDBM258594(US9493490, Example 3 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 50nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 3149BDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50055668BDBM50055668(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 27225BDBM27225((2R)-6-amino-2-(6-{[(2S,3S,4R,5R)-5-(6-amino-9H-pu...)
Affinity DataIC50: 54nMAssay Description:Inhibition of PKACalpha in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50311407BDBM50311407(N-((6R,9R,19R)-1-amino-19-(4-aminobutyl)-6-carbamo...)
Affinity DataIC50: 61nMAssay Description:Inhibition of PKACalpha in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773706BDBM773706(D0025 | US20250299772, Compound 4)
Affinity DataIC50: 62nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 773705BDBM773705(D0135 | US20250299772, Compound 3)
Affinity DataIC50: 63nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/12/2026
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 687755BDBM687755(US20240246972, Compound 2 | Synthesis of N-(2-fluo...)
Affinity DataIC50: 63.3nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

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