Compile Data Set for Download or QSAR
Found 27 of ki for UniProtKB: P31749
LigandPNGBDBM15131(5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...)
Affinity DataKi:  0.160nM ΔG°:  -13.2kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15136(5-indazolyl pyridine 11e | 5-{5-[(2S)-2-amino-3-(2...)
Affinity DataKi:  1.10nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15132(5-indazolyl pyridine 11a | 5-{5-[(2S)-2-amino-3-(2...)
Affinity DataKi:  2.10nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15134(5-indazolyl pyridine 11c | 5-{5-[(2S)-2-amino-3-(n...)
Affinity DataKi:  3.20nM ΔG°:  -11.5kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15125(5-isoquinolinyl pyridine 10d | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  3.5nM ΔG°:  -11.4kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15133(5-indazolyl pyridine 11b | 5-{5-[(2S)-2-amino-3-(1...)
Affinity DataKi:  6.60nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15123(5-isoquinolinyl pyridine 10b | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  6.80nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15145(5-indazolyl pyridine 16 | N-[(2S)-2-amino-3-phenyl...)
Affinity DataKi:  8.30nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM15135(5-indazolyl pyridine 11d | 5-{5-[(2S)-2-amino-3-(n...)
Affinity DataKi:  8.30nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15138(5-indazolyl pyridine 11g | 5-{5-[(2S)-2-amino-3-ph...)
Affinity DataKi:  11nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15122(5-isoquinolinyl pyridine 10a | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  54.6nM ΔG°:  -9.80kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15124(5-isoquinolinyl pyridine 10c | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  63.7nM ΔG°:  -9.71kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15144(5-(5-{[(2S)-2-amino-5-phenylpentyl]oxy}pyridin-3-y...)
Affinity DataKi:  70.6nM ΔG°:  -9.65kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15126(5-isoquinolinyl pyridine 10e | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  85nM ΔG°:  -9.54kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15127(5-isoquinolinyl pyridine 10f | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  89.6nM ΔG°:  -9.51kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15137(3-[(2S)-2-amino-3-{[5-(3-methyl-1H-indazol-5-yl)py...)
Affinity DataKi:  185nM ΔG°:  -9.09kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15143(5-(5-{[(4R)-4-amino-5-phenylpentyl]oxy}pyridin-3-y...)
Affinity DataKi:  197nM ΔG°:  -9.05kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15141(5-indazolyl pyridine 11j | 5-{5-[(2S)-2-amino-2-ph...)
Affinity DataKi:  233nM ΔG°:  -8.95kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15146(5-(5-{[(2S)-2-amino-3-(1H-indol-3-yl)propyl]sulfan...)
Affinity DataKi:  244nM ΔG°:  -8.92kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM15142(5-indazolyl pyridine 11k | 5-{5-[(3S)-3-amino-4-ph...)
Affinity DataKi:  289nM ΔG°:  -8.82kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15140(5-indazolyl pyridine 11i | 5-{5-[(2S)-2-amino-3-cy...)
Affinity DataKi:  368nM ΔG°:  -8.68kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15130(5-isoquinolinyl pyridine 10i | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  465nM ΔG°:  -8.55kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15147(5-indazolyl pyridine 24 | 5-{5-[(2R)-2-amino-3-phe...)
Affinity DataKi:  626nM ΔG°:  -8.37kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15129(5-isoquinolinyl pyridine 10h | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  672nM ΔG°:  -8.33kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15128(5-isoquinolinyl pyridine 10g | 6-{5-[(2S)-2-amino-...)
Affinity DataKi:  1.53E+3nM ΔG°:  -7.85kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15139(5-indazolyl pyridine 11h | 5-{5-[(2S)-2-amino-3-(p...)
Affinity DataKi:  3.28E+3nM ΔG°:  -7.40kcal/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed