Compile Data Set for Download or QSAR
maximum 50k data
Found 50 of ic50 for UniProtKB: Q9WUI1
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16530(2-arylpyridazin-3-one, 36 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  2nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421141(CHEMBL2088578)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421140(CHEMBL2088591)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50317579(6-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-2H-q...)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421137(CHEMBL2088588)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16524(2-arylpyridazin-3-one, 30 | 2-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  15nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50317588(6-(2,4-difluorophenyl)-1-(2-fluoro-5-(5-methyl-1,3...)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Mus musculus)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50219251(CHEMBL423071)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against p38 kinase (40 ng/well) was determined in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50317583(1-(2,6-difluoro-4-(5-methyl-1,3,4-oxadiazol-2-yl)p...)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16525(2-arylpyridazin-3-one, 31 | 2-{3-[(2-chloro-4-fluo...)
Affinity DataIC50:  20nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421127(CHEMBL2088582)
Affinity DataIC50:  27nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122916(6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...)
Affinity DataIC50:  28nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16527(2-arylpyridazin-3-one, 33 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  29nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16529(2-arylpyridazin-3-one, 35 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  29nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16528(2-arylpyridazin-3-one, 34 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  31nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421133(CHEMBL2088575)
Affinity DataIC50:  36nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16526(2-amino-N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-...)
Affinity DataIC50:  41nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122920(6-[2-(2,3-Dichloro-phenyl)-imidazo[1,2-a]pyridin-3...)
Affinity DataIC50:  44nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421132(CHEMBL2088579)
Affinity DataIC50:  53.5nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122915(2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...)
Affinity DataIC50:  63nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122922(6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...)
Affinity DataIC50:  64nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421139(CHEMBL2088590)
Affinity DataIC50:  64nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421128(CHEMBL2088583)
Affinity DataIC50:  66nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122914(6-(2-(2,4-difluorophenyl)imidazo[1,2-a]pyridin-3-y...)
Affinity DataIC50:  78nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421125(CHEMBL2088586)
Affinity DataIC50:  86nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122908(6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...)
Affinity DataIC50:  94nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421138(CHEMBL2088589)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122918(2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...)
Affinity DataIC50:  112nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16521(2-arylpyridazin-3-one, 27 | 6-[(2-chloro-4-fluorop...)
Affinity DataIC50:  135nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421136(CHEMBL2088587)
Affinity DataIC50:  140nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122913(6-[2-(2,4-Difluoro-phenyl)-imidazo[1,2-a]pyridin-3...)
Affinity DataIC50:  140nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122910(2-(2,6-Dichloro-phenyl)-6-[2-(4-fluoro-phenyl)-imi...)
Affinity DataIC50:  153nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122923(6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...)
Affinity DataIC50:  171nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421134(CHEMBL2088576)
Affinity DataIC50:  180nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421130(CHEMBL2088580)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16522(2-arylpyridazin-3-one, 28 | 6-[(3-aminopropyl)(2-c...)
Affinity DataIC50:  211nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421135(CHEMBL2088577)
Affinity DataIC50:  230nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421126(CHEMBL2088585)
Affinity DataIC50:  300nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122921(2-(2-Chloro-phenyl)-6-[2-(3-trifluoromethyl-phenyl...)
Affinity DataIC50:  355nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421129(CHEMBL2088584)
Affinity DataIC50:  400nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16517(2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,...)
Affinity DataIC50:  450nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16515(2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-d...)
Affinity DataIC50:  450nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16523(2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...)
Affinity DataIC50:  600nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122911(6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...)
Affinity DataIC50:  670nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16518(2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl...)
Affinity DataIC50:  850nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122912(2-(2,6-Dichloro-phenyl)-6-[2-(2,3-dichloro-phenyl)...)
Affinity DataIC50:  890nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16516(2-(2-chlorophenyl)-6-[(2-methoxyphenyl)amino]-2,3-...)
Affinity DataIC50:  920nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16513(2-(2-chlorophenyl)-6-[(2-chlorophenyl)amino]-2,3-d...)
Affinity DataIC50:  990nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50122919(6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM50421131(CHEMBL2088581)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed