Compile Data Set for Download or QSAR
Report error Found 2222 of ic50 for UniProtKB: P25103
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140783(2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic ac...)
Affinity DataIC50: 0.000100nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140770(2-Aminomethyl-4-phenyl-quinoline-3-carboxylic acid...)
Affinity DataIC50: 0.00170nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140773(2-Bromomethyl-4-phenyl-quinoline-3-carboxylic acid...)
Affinity DataIC50: 0.0100nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140785(2-Methylaminomethyl-4-phenyl-quinoline-3-carboxyli...)
Affinity DataIC50: 0.0110nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50067935((2S,3S)-N-(2-methoxy-5-(trifluoromethoxy)benzyl)-2...)
Affinity DataIC50: 0.0120nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataIC50: 0.0126nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataIC50: 0.0126nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50314371((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.0130nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364189(CHEMBL1951813)
Affinity DataIC50: 0.0170nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364190(CHEMBL1951810)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364190(CHEMBL1951810)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357169(CHEMBL1917866)
Affinity DataIC50: 0.0250nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM47085(US8592454, 71b)
Affinity DataIC50: 0.0270nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106978(US8592454, 176)
Affinity DataIC50: 0.0290nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106983(US8592454, 420)
Affinity DataIC50: 0.0300nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140786(4-Phenyl-quinoline-3-carboxylic acid (3,5-bis-trif...)
Affinity DataIC50: 0.0300nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50220124(1-(4-((3S,4R)-3-(5-(2-(3,5-bis(trifluoromethyl)phe...)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106974(US8592454, 25)
Affinity DataIC50: 0.0310nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106979(US8592454, 192)
Affinity DataIC50: 0.0320nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364202(CHEMBL1951626)
Affinity DataIC50: 0.0320nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364195(CHEMBL1951633)
Affinity DataIC50: 0.0350nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106982(US8592454, 378)
Affinity DataIC50: 0.0390nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357186(CHEMBL1917853)
Affinity DataIC50: 0.0390nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50442587(CHEMBL2441370)
Affinity DataIC50: 0.0400nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50314389((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.0410nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364197(CHEMBL1951631)
Affinity DataIC50: 0.0430nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357159(CHEMBL1917856)
Affinity DataIC50: 0.0440nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364192(CHEMBL1951811)
Affinity DataIC50: 0.0460nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364198(CHEMBL1951630)
Affinity DataIC50: 0.0470nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364196(CHEMBL1951632)
Affinity DataIC50: 0.0480nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106980(US8592454, 233)
Affinity DataIC50: 0.0490nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357185(CHEMBL1917852)
Affinity DataIC50: 0.0490nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052278(5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125 I]-Tyr8 SP from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50220121((3R,4S)-N-(2-(3,5-bis(trifluoromethyl)phenyl)propa...)
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50220132((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...)
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052278(5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of substance P binding to Tachykinin receptor 1 in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052278(5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125I]-labeled SP from human NK-1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364199(CHEMBL1951629)
Affinity DataIC50: 0.0520nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357168(CHEMBL1917865)
Affinity DataIC50: 0.0540nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357184(CHEMBL1917851)
Affinity DataIC50: 0.0540nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357162(CHEMBL1917859)
Affinity DataIC50: 0.0560nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357163(CHEMBL1917860)
Affinity DataIC50: 0.0570nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357165(CHEMBL1917862)
Affinity DataIC50: 0.0570nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50218239((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50234162((6R,7S,7aS)-6-{(1R)-1-[3,5-bis(trifluoromethyl)phe...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50313630((6R,7S,7aS)-2-((1H-pyrazol-5-yl)methylamino)-6-((R...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50313627((6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 2222 total ) | Next | Last >>
Jump to: