Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of ic50 for UniProtKB: P28472
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataIC50:  17nMAssay Description:Binding affinity to human recombinant GABAA alpha5beta3gamma2 expressed in Xenopous laevis oocytes by patch clamp techniqueMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50106148(5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]-EBOB binding to drosophila GABA-A receptor (range 1-28)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50106149(1-(2,6-Dichloro-4-trifluoromethyl-phenyl)-4-(3-tri...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]-EBOB binding to human GABA-A receptor beta3 subunit (range 1-28)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50106149(1-(2,6-Dichloro-4-trifluoromethyl-phenyl)-4-(3-tri...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]-EBOB binding to human GABA-A receptor beta3 subunit (range 1-28)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50106148(5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]-EBOB binding to drosophila GABA-A receptor (range 1-28)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.00E+3nMAssay Description:Negative allosteric modulation activity at human GABAA alpha4beta3gamma2 stably expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50395121(CHEMBL2163548)
Affinity DataIC50:  3.90E+3nMAssay Description:Displacement of [3H]R-(-)-14 from human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  5.50E+3nMAssay Description:Negative allosteric modulation activity at human GABAA alpha3beta3gamma2 stably expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.57E+4nMAssay Description:Negative allosteric modulation activity at human GABAA alpha2beta3gamma2 stably expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.94E+4nMAssay Description:Negative allosteric modulation activity at human GABAA alpha5beta3gamma2 stably expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50055935(5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidi...)
Affinity DataIC50:  8.80E+4nMAssay Description:Displacement of [3H]R-(-)-14 from human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGamma-aminobutyric acid receptor subunit beta-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50395120(CHEMBL2163549)
Affinity DataIC50:  1.70E+5nMAssay Description:Displacement of [3H]R-(-)-14 from human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed