TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: 2.61nMAssay Description:Binding affinity to GABAA alpha-4-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.10nM ΔG°: -11.5kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin-Milwaukee
University of Wisconsin-Milwaukee
Affinity DataKi: 5.30nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]-Ro-15-1788 from human GABA-A receptor alpha4 subunit expressed in L(tk) cellsMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 38.8nMAssay Description:Binding affinity to human recombinant GABA alpha4beta3gamma2 receptorMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha3-beta3-gamma2 subunits expressed in L(tk-)cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 114nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 119nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 137nMAssay Description:Agonist activity at human recombinant GABAA alpha4beta3gamma2 receptor expressed in Xenopus oocytes at 1 to 10 uM by patch clamp techniqueMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 159nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 175nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 175nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 195nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha4beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 213nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 244nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to human alpha4-beta3-gamma2 GABA-A receptor expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 291nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
Affinity DataKi: >300nMAssay Description:Binding affinity to GABAA alpha-4-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: >300nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha4beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Homo sapiens (Human))
Moltech
Curated by ChEMBL
Moltech
Curated by ChEMBL
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: >333nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: >333nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: >333nMAssay Description:Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid s...More data for this Ligand-Target Pair