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Found 7 of ic50 for UniProtKB: Q62868
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50614317(CHEMBL5281208)
Affinity DataIC50:  240nMAssay Description:Inhibition of ROCK2 in rat A7R5 cells assessed as MLC phosphorylation at T18/S19 by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM15211(CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...)
Affinity DataIC50:  270nMAssay Description:Inhibition of rat ROCK2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  800nMAssay Description:Inhibition of rat ROCK2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  820nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  940nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  1.60E+3nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of rat ROCK2 expressed in Sf9 cellsMore data for this Ligand-Target Pair