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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)
Affinity DataKi:  0.398nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50427452(CHEMBL2326941)
Affinity DataKi:  0.631nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi:  5nMAssay Description:Activity at Histamine H1 receptor using functional H1 receptor assay on guinea pig ileumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14381(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  5.20nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50314557((4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14379(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-tert...)
Affinity DataKi:  5.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14382(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  7.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14365(8-(1-Benzyloxy-1-methyl-ethyl)-3-(3-cyclopentyloxy...)
Affinity DataKi:  8.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14386(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  9.5nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14378(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-di...)
Affinity DataKi:  9.70nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  9.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14368(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  10.3nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14370(8-{1-[(4-Chlorobenzyl)oxy]-1-methyl-ethyl}-3-[3-cy...)
Affinity DataKi:  11nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14366(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(2-meth...)
Affinity DataKi:  11nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14372(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-fluo...)
Affinity DataKi:  11.6nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14367(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-meth...)
Affinity DataKi:  13nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14375((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  17.3nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14371(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(2-fluo...)
Affinity DataKi:  18.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14376(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-me...)
Affinity DataKi:  21.4nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14374((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  21.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14380(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...)
Affinity DataKi:  26.6nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50029954((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...)
Affinity DataKi:  27nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50048248((3S,4R)-3-Acetyl-4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470745(CHEMBL286840)
Affinity DataKi:  30nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285059(1-(tert-butyl) 3-methyl 4-(3-cyclopentyloxy-4-meth...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50453147(CHEMBL4202704)
Affinity DataKi:  32nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14384(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...)
Affinity DataKi:  33nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470752(CHEMBL38328)
Affinity DataKi:  34nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285045(1-isopropyl 3-methyl 4-(3-cyclopentyloxy-4-methoxy...)
Affinity DataKi:  40nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50314558((4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamin...)
Affinity DataKi:  41nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14373((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  42.8nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470756(CHEMBL37453)
Affinity DataKi:  46nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14385(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  46.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285042(CHEMBL302632 | tert-butyl 3-(3-cyclopentyloxy-4-me...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285038(1-benzyl 3-methyl 4-(3-cyclopentyloxy-4-methoxyphe...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470750(CHEMBL286291)
Affinity DataKi:  56nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470731(CHEMBL146946)
Affinity DataKi:  59nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285050(CHEMBL59386 | methyl 3-(3-cyclopentyloxy-4-methoxy...)
Affinity DataKi:  60nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470736(CHEMBL37029)
Affinity DataKi:  60nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50029955((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...)
Affinity DataKi:  63nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470740(CHEMBL264851)
Affinity DataKi:  65nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470754(CHEMBL288928)
Affinity DataKi:  68nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50029951((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...)
Affinity DataKi:  70nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470743(CHEMBL422578)
Affinity DataKi:  71nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470725(CHEMBL36318)
Affinity DataKi:  71nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM14377(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-cyan...)
Affinity DataKi:  71.3nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50314583((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  77nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285057(CHEMBL61876 | tert-butyl 3-(3-cyclopentyloxy-4-met...)
Affinity DataKi:  80nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50285041(CHEMBL301053 | methyl 3-cyano-4-(3-cyclopentyloxy-...)
Affinity DataKi:  80nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50470735(CHEMBL287687)
Affinity DataKi:  89nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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