Affinity DataEC50: 1.10nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: >2nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Inhibition of human SGLT2 expressed in xenopus oocytes assessed as inhibition of [14C]AMG uptakeMore data for this Ligand-Target Pair
Affinity DataEC50: 6.60nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 6.60nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataEC50: 35.6nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Inhibition of human SGLT2 expressed in Xenopus oocyte assessed as [14C]alpha-methyl glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 67nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 77nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 88nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
