Compile Data Set for Download or QSAR
Found 4 of kd for UniProtKB: P18901
TargetD(1A) dopamine receptor(RAT)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Show SMILES CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
Affinity DataKd:  0.300nMAssay Description:Binding affinity against dopamine receptor D1 in rat striatum using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016794(8-Chloro-5-(4-iodo-phenyl)-3-methyl-2,3,4,5-tetrah...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccc(I)cc1
Show InChI InChI=1S/C17H17ClINO/c1-20-7-6-12-8-16(18)17(21)9-14(12)15(10-20)11-2-4-13(19)5-3-11/h2-5,8-9,15,21H,6-7,10H2,1H3
Affinity DataKd:  1.40nMAssay Description:In vitro binding affinity to the rat striatal homogenateMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016792(8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-be...)
Show SMILES CN1CCc2cc(Br)c(O)cc2[C@H](C1)c1ccccc1
Show InChI InChI=1S/C17H18BrNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1
Affinity DataKd:  2.30nMAssay Description:Compound was evaluated in vitro for the binding affinity to the rat striatal homogenate.More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016795(3-Methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Show SMILES CN1CCc2ccc(O)cc2[C@H](C1)c1ccccc1
Show InChI InChI=1S/C17H19NO/c1-18-10-9-14-7-8-15(19)11-16(14)17(12-18)13-5-3-2-4-6-13/h2-8,11,17,19H,9-10,12H2,1H3/t17-/m1/s1
Affinity DataKd:  197nMAssay Description:Compound was evaluated in vitro for the binding affinity to the rat striatal homogenate.More data for this Ligand-Target Pair