Compile Data Set for Download or QSAR
maximum 50k data
Found 54 of kd for UniProtKB: Q9JI35
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKd:  0.158nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118159(CHEMBL340932 | Dicyclopropylmethyl-carbamic acid 3...)
Affinity DataKd:  1nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85830(VUF5202)
Affinity DataKd:  1.26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKd:  1.26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50411494(CHEMBL429458)
Affinity DataKd:  1.26nMAssay Description:Antagonist activity at histamine H3 receptor in guinea pig ileum assessed as inhibition of (R)-methyl histamine induced longitudinal smooth muscle co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441644(CHEMBL2437423)
Affinity DataKd:  1.30nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441642(CHEMBL2437425)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441641(CHEMBL2437426)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441637(CHEMBL2437430)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50411492(CHEMBL394144)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in guinea pig ileum assessed as inhibition of (R)-methyl histamine induced longitudinal smooth muscle co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441646(CHEMBL2437421)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441643(CHEMBL2437424)
Affinity DataKd:  2.5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228551(4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propox...)
Affinity DataKd:  3.98nMAssay Description:Antagonist activity at histamine H3 receptor in guinea pig ileum assessed as inhibition of (R)-methyl histamine induced longitudinal smooth muscle co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKd:  3.98nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441638(CHEMBL2437429)
Affinity DataKd:  5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22916(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Affinity DataKd:  5.01nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50247053(1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...)
Affinity DataKd:  5.62nMAssay Description:Antagonist activity at histamine H3 receptor in isolated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409211(CHEMBL45027)
Affinity DataKd:  6.17nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441640(CHEMBL2437427)
Affinity DataKd:  6.30nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441651(CHEMBL2437417)
Affinity DataKd:  7.90nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409217(CHEMBL45056)
Affinity DataKd:  7.94nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409576(CHEMBL130850)
Affinity DataKd:  10nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441653(CHEMBL2437432)
Affinity DataKd:  10nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407372(CHEMBL44220)
Affinity DataKd:  10nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441647(CHEMBL2437420)
Affinity DataKd:  10nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409578(CHEMBL2112321)
Affinity DataKd:  12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118155((1,2,2-Trimethyl-propyl)-carbamic acid 3-(1H-imida...)
Affinity DataKd:  12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409577(CHEMBL336499)
Affinity DataKd:  12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118161((1-tert-Butyl-2,2-dimethyl-propyl)-carbamic acid 3...)
Affinity DataKd:  12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441639(CHEMBL2437428)
Affinity DataKd:  13nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118157(CHEMBL128635 | [1-(1-Methyl-cyclopropyl)-ethyl]-ca...)
Affinity DataKd:  15.8nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126878(1-[4-(4-Imidazol-1-yl-phenoxymethyl)-benzyl]-piper...)
Affinity DataKd:  15.8nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50441654(CHEMBL2437431)
Affinity DataKd:  16nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126902(1-[4-(4-Pyrrolidin-1-ylmethyl-benzyloxy)-phenyl]-e...)
Affinity DataKd:  18.2nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370139(CHEMBL1788247)
Affinity DataKd:  19.9nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118162((Cyclopropyl-phenyl-methyl)-carbamic acid 3-(1H-im...)
Affinity DataKd:  19.9nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118160((1-Cyclopropyl-ethyl)-carbamic acid 3-(1H-imidazol...)
Affinity DataKd:  19.9nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409580(CHEMBL131366)
Affinity DataKd:  19.9nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKd:  25.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118151(4-[3-(4,4-Dimethyl-pentyloxy)-propyl]-1H-imidazole...)
Affinity DataKd:  25.1nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126900(1-[4-(4-Azepan-1-ylmethyl-benzyloxy)-phenyl]-ethan...)
Affinity DataKd:  30.9nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126875(CHEMBL39951 | Cyclopentyl-[4-(4-piperidin-1-ylmeth...)
Affinity DataKd:  30.9nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126888(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-benzyl]-pi...)
Affinity DataKd:  38.0nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118152(4-[3-(5,5-Dimethyl-hexyloxy)-propyl]-1H-imidazole;...)
Affinity DataKd:  39.8nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118150(4-[3-(1,3,3-Trimethyl-butoxy)-propyl]-1H-imidazole...)
Affinity DataKd:  50.1nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409218(CHEMBL45342)
Affinity DataKd:  50.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409200(CHEMBL412882)
Affinity DataKd:  61.7nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataKd:  61.7nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126895(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataKd:  85.1nMAssay Description:Potency at histamine H3 receptor subtype, was tested on guinea pig right ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(GUINEA PIG)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50118153((Cyclohexyl-phenyl-methyl)-carbamic acid 3-(1H-imi...)
Affinity DataKd:  100nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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