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TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  56nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32381(adenosine-derived inhibitor (Grp78), 14 | adenosin...)
Affinity DataKd:  60nM Kon:  0.0400M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataKd:  80nM Kon:  0.0900M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50617261(CHEMBL5414287)
Affinity DataKd:  110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32375(adenosine-derived inhibitor (Grp78), 9 | adenosine...)
Affinity DataKd:  230nM Kon:  0.200M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32376(adenosine-derived inhibitor (Grp78), 11 | adenosin...)
Affinity DataKd:  250nM Kon:  0.400M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd:  334nMAssay Description:Binding affinity to HspA5 (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652104(CHEMBL5639838)
Affinity DataKd:  679nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32377(adenosine-derived inhibitor (Grp78), 12 | adenosin...)
Affinity DataKd:  770nM Kon:  0.300M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32373(adenosine-derived inhibitor (Grp78), 8 | adenosine...)
Affinity DataKd:  990nM Kon:  0.5M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM82125((2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-...)
Affinity DataKd:  990nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  1.85E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM82124(adenosine-derived inhibitor (Grp78), 1)
Affinity DataKd:  2.17E+3nM Kon:  0.00500M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM82129((2R,3R,4S,5R)-2-{6-Amino-8-[(quinolin-2-ylmethyl)a...)
Affinity DataKd:  2.41E+3nM Kon:  0.400M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM82127((2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-...)
Affinity DataKd:  2.71E+3nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM82126((2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-...)
Affinity DataKd:  4.36E+3nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32370(adenosine-derived inhibitor (Grp78), 2 | adenosine...)
Affinity DataKd:  6.80E+3nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM32371(adenosine-derived inhibitor (Grp78), 3 | adenosine...)
Affinity DataKd:  7.46E+3nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM82128(2-[(2R,3S,4R,5R)-5-(6-Amino-8-methylaminopurin-9-y...)
Affinity DataKd:  1.24E+4nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50617256(CHEMBL5415251)
Affinity DataKd:  2.50E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed