TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.00200nMAssay Description:Evaluated for gonadotropin-releasing hormone receptor binding by displacing the 50% of the bound tracer [125I]-[D-Lys6]-GnRH radioligand in rat pitui...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.0560nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Evaluated for gonadotropin-releasing hormone receptor binding by displacing the 50% of the bound tracer [125I]-[D-Lys6]-GnRH radioligand in rat pitui...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Evaluated for gonadotropin-releasing hormone receptor binding by displacing the 50% of the bound tracer [125I]-[D-Lys6]-GnRH radioligand in rat pitui...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Binding affinity at rat GnRH receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Evaluated for gonadotropin-releasing hormone receptor binding by displacing the 50% of the bound tracer [125I]-[D-Lys6]-GnRH radioligand in rat pitui...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Displacement of [125I]leuprorelin from rat GnRH receptor expressed in CHO cells after 60 mins by X-ray counterMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Displacement of [125I]leuprorelin from rat GnRH receptor expressed in CHO cells after 60 mins by X-ray counter in presence of 40% fetal bovine serumMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for its inhibitory activity against rat pituitary Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]-buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranesMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Institute Of Science
Curated by ChEMBL
Institute Of Science
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair