Found 50 of ec50 data for polymerid = 50001025,50006406,50007714 
Affinity DataEC50: 22nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 165nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 212nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 221nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 243nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 334nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 348nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 365nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 411nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 424nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 512nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 677nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 743nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 861nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 2.20E+3nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 6.66E+3nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 7.02E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.16E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.17E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.17E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.17E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.17E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.18E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.18E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.19E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.20E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.23E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.24E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.24E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.24E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.25E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.27E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.29E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.32E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.37E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.42E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
Affinity DataEC50: 7.43E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 8.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Antiprion activity against sheep prion infected in mouse ScN2a-cl3 cells assessed as reduction in PrPSc level after 5 days by ELISAMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
