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Found 6 of ki for UniProtKB: P24008
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50031895((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50031877((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50031896((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50368782(Bexlosteride | CHEMBL24955 | LY-191704)
Affinity DataKi:  8nMAssay Description:Binding affinity on rat 5-alpha reductase-1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50289143((5R,10R,14S)-17-(2-Hydroxy-1-methyl-ethyl)-10-meth...)
Affinity DataKi:  35nMAssay Description:Apparent inhibitory activity of the compound was determined against rat prostatic Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails Article