Compile Data Set for Download or QSAR
maximum 50k data
Found 82 of ic50 for UniProtKB: P41252
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290686(9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-...)
Affinity DataIC50:  0.800nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217841(REVEROMYCIN A)
Affinity DataIC50:  4.46nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366870(CHEMBL605376)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  15nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479281(2,3-DIHYDROREVEROMYCIN A)
Affinity DataIC50:  17.5nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  20nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479274(4-HYDROXY REVEROMYCIN A)
Affinity DataIC50:  21.7nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479284(CHEMBL442945)
Affinity DataIC50:  36.9nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366862(CHEMBL605592)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  45nMAssay Description:Compound tested for the inhibition of human Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479277(2,3-DIHYDRO-5-EPIREVEROMYCIN A)
Affinity DataIC50:  88nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50222902(CHEMBL1163069)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217935(CHEMBL114859)
Affinity DataIC50:  100nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290689(9-{(E)-4-[(2S,3R,4R,5S)-5-(3-Chloro-propane-1-sulf...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  110nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075062(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  120nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217844(CHEMBL115953)
Affinity DataIC50:  168nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  200nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075062(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  240nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  300nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290688(9-{(E)-4-[(2S,3R,4R,5S)-5-(3-Chloro-benzenesulfony...)
Affinity DataIC50:  300nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290687(9-{(E)-4-[(2S,3R,4R,5S)-5-(Butane-1-sulfonylamino)...)
Affinity DataIC50:  300nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479282(CHEMBL505238)
Affinity DataIC50:  312nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)
Affinity DataIC50:  330nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  370nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  400nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479276(CHEMBL461144)
Affinity DataIC50:  433nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217849(CHEMBL115317)
Affinity DataIC50:  554nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479275(5-EPIREVEROMYCIN A)
Affinity DataIC50:  572nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217839(CHEMBL327131)
Affinity DataIC50:  801nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479273(CHEMBL498825)
Affinity DataIC50:  995nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  1.02E+3nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366874(CHEMBL605809)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479280(SPIROFUNGIN A)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479272(CHEMBL455272)
Affinity DataIC50: >1.29E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217937(CHEMBL114949)
Affinity DataIC50: >1.42E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479279(CHEMBL510665)
Affinity DataIC50: >1.48E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217842(REVEROMYCIN B)
Affinity DataIC50: >1.51E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479270(CHEMBL499655)
Affinity DataIC50: >1.57E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479283(CHEMBL508146)
Affinity DataIC50: >1.65E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479269(CHEMBL471857)
Affinity DataIC50: >1.73E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479271(CHEMBL515541)
Affinity DataIC50: >1.86E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479268(SPIROFUNGIN B)
Affinity DataIC50: >1.98E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479278(CHEMBL462123)
Affinity DataIC50: >2.01E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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