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Found 33 of ic50 for UniProtKB: P24046
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Affinity DataIC50:  2.22E+3nMAssay Description:Antagonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Affinity DataIC50:  2.22E+3nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Affinity DataIC50:  5.40E+3nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50032973(((Z)-3-Amino-propenyl)-methyl-phosphinic acid | 3-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492303(CHEMBL2398121)
Affinity DataIC50:  6.60E+3nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492306(CHEMBL2398115)
Affinity DataIC50:  9.60E+3nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428278(CHEMBL446306)
Affinity DataIC50:  9.76E+3nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492304(CHEMBL2398120)
Affinity DataIC50:  1.29E+4nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50240386(5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...)
Affinity DataIC50:  1.29E+4nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50374650(CHEMBL257443)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Affinity DataIC50:  1.71E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50336851(3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...)
Affinity DataIC50:  1.99E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50336850(3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...)
Affinity DataIC50:  2.97E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428276(CHEMBL2337487)
Affinity DataIC50:  5.86E+4nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428275(CHEMBL2337889)
Affinity DataIC50:  7.65E+4nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492305(CHEMBL2398122)
Affinity DataIC50:  8.15E+4nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50243875(CHEMBL451118 | cis-3-Amino-cyclobutyl(methyl)phosp...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50243876(CHEMBL447036 | trans-3-Amino-cyclobutyl(methyl)pho...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50525195(CHEMBL4586460)
Affinity DataIC50:  1.00E+5nMAssay Description:Antagonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428276(CHEMBL2337487)
Affinity DataIC50:  1.03E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492302(CHEMBL2398114)
Affinity DataIC50:  1.15E+5nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428275(CHEMBL2337889)
Affinity DataIC50:  1.48E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492299(CHEMBL2398123)
Affinity DataIC50:  1.53E+5nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428277(CHEMBL2337486)
Affinity DataIC50:  1.93E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50428277(CHEMBL2337486)
Affinity DataIC50:  2.81E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50525193(CHEMBL4455221)
Affinity DataIC50:  3.00E+5nMAssay Description:Antagonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50525186(CHEMBL4566832)
Affinity DataIC50:  3.00E+5nMAssay Description:Antagonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492301(CHEMBL2398116)
Affinity DataIC50:  4.08E+5nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50492300(CHEMBL2398117)
Affinity DataIC50:  5.70E+5nMAssay Description:Antagonist activity at human recombinant GABAA rho1 receptor expressed in Xenopus laevis assessed as inhibition of GABA-induced chloride current prod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50241194((1S,2R)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataIC50: >8.00E+5nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50374649(CHEMBL257442)
Affinity DataIC50:  8.90E+5nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed