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Found 33 of ic50 for UniProtKB: P24433
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075146((E)-3-(2,5-Dimethyl-thiophen-3-yl)-N-[(S)-1-(5-met...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075158((E)-3-(5-Bromo-thiophen-2-yl)-N-[(S)-1-(5-methyl-4...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075166((E)-3-(2,6-Dichloro-phenyl)-N-[(S)-1-(5-methyl-4-o...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075152((E)-3-(2-Chloro-4-hydroxy-phenyl)-N-[(S)-1-(5-meth...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075154((E)-3-(2-Ethoxy-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075163((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075138((E)-3-(5-Chloro-thiophen-2-yl)-N-[(S)-1-(5-methyl-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075159((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075165((E)-3-(3,5-Dimethoxy-phenyl)-N-[(S)-1-(5-methyl-4-...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075148((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075136((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075167((E)-3-(4-Bromo-thiophen-2-yl)-N-[(S)-1-(5-methyl-4...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075143((E)-3-(2-Chloro-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075137((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075156((E)-3-(2-Chloro-6-fluoro-phenyl)-N-[(S)-1-(5-methy...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075151(CHEMBL141722 | N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075164((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075161((E)-3-(4-Dimethylamino-phenyl)-N-[(S)-1-(5-methyl-...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075157((E)-3-(2-Bromo-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4H...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075162((E)-3-(5-Bromo-furan-2-yl)-N-[(S)-1-(5-methyl-4-ox...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075169((E)-3-(3-Chloro-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...)
Affinity DataIC50:  42nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075142(CHEMBL138470 | N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[...)
Affinity DataIC50:  42nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075155((E)-3-(2-Bromo-thiophen-3-yl)-N-[(S)-1-(5-methyl-4...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075149((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  54nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075168((E)-3-(3-Bromo-thiophen-2-yl)-N-[(S)-1-(5-methyl-4...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075145((E)-3-(2,6-Difluoro-phenyl)-N-[(S)-1-(5-methyl-4-o...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075144((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075141((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  76nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075140((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075153((E)-3-(4-Formyl-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...)
Affinity DataIC50:  94nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075150((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075139((E)-3-(2,6-Dimethoxy-phenyl)-N-[(S)-1-(5-methyl-4-...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075147((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed