TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2C receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+3nMAssay Description:Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 2.70E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 4.70E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2C receptor (unknown origin) assessed as increase in glutamate-induced calcium flux measured at time inte...More data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 7.40E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2C NMDAR (unknown origin) expressed in Dox-inducible cells by BD calcium indicator dye based-fluorescence...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluN1a/GluN2C (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 8.30E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2C receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair