Compile Data Set for Download or QSAR
maximum 50k data
Found 583 of ic50 data for polymerid = 50003540
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453006(CHEMBL4217624)
Affinity DataIC50:  609nMAssay Description:Inhibition of biotinylated VEGF-A binding to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50467383(CHEMBL4279036)
Affinity DataIC50:  800nMAssay Description:Inhibition of biotinylated VEGF165 binding to NRP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453006(CHEMBL4217624)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of biotinylated VEGF-A binding to human NRP1 expressed in human DU145 cells after 2 hrsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188998(5-chloro-2-(3-methoxyphenyl)-3-(phenethylamino)ind...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188994(5-chloro-2-(3-fluorophenyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188970(5-chloro-2-(4-chlorophenyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50189004(5-chloro-2-phenethyl-3-(phenethylamino)indolizine-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188974(5-chloro-3-(phenethylamino)-2-(pyridin-2-yl)indoli...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188968(5-chloro-3-(phenethylamino)-2-phenylindolizine-1-c...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50512569(CHEMBL4476643)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of biotinylated human VEGF-A165 binding to recombinant human NRP1 receptor after 2 hrs by chemiluminescence analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50512569(CHEMBL4476643)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of biotinylated human VEGF-A165 binding to recombinant human NRP1 receptor after 2 hrs by chemiluminescence analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188990(5-chloro-2-(2-fluorophenyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188979(3-(2-chlorophenethylamino)-5-chloro-2-phenylindoli...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188985(5-chloro-2-(3-chlorophenyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188971(5-chloro-2-(4-(methylthio)phenyl)-3-(phenethylamin...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188969(5-chloro-2-(2-methoxyphenyl)-3-(phenethylamino)ind...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of biotinylated-VEGF-A125 from NRP1 b1 domain by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188967(5-chloro-2-(2-chlorophenyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in human DU145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50189000(3-(4-chlorophenethylamino)-5-chloro-2-phenylindoli...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188982(5-chloro-3-(phenethylamino)-2-(pyridin-3-yl)indoli...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188999(5-chloro-2-(4-fluoronaphthalen-1-yl)-3-(phenethyla...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188983(3-(2-(benzyl(methyl)amino)ethylamino)-5-chloro-2-p...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313483(CHEMBL1091089 | H-KPPR-OH)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of biotinylated VEGF165 binding to NRP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188975(5-chloro-2-(4-fluorophenyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50189003(5-chloro-3-(phenethylamino)-2-p-tolylindolizine-1-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188972(5-chloro-2-(4-methoxyphenyl)-3-(phenethylamino)ind...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50512567(CHEMBL4586661)
Affinity DataIC50:  5.37E+3nMAssay Description:Inhibition of biotinylated human VEGF-A165 binding to recombinant human NRP1 receptor after 2 hrs by chemiluminescence analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50512567(CHEMBL4586661)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of biotinylated human VEGF-A165 binding to recombinant human NRP1 receptor after 2 hrs by chemiluminescence analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188992(5-chloro-3-(phenethylamino)-2-(pyridin-4-yl)indoli...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313494((S)-2-[(3-{3-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188984(5-chloro-2-(3-mercaptophenyl)-3-(phenethylamino)in...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188997(5-chloro-2-(2,5-dimethylphenyl)-3-(phenethylamino)...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  7.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50512570(CHEMBL4549611)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of biotinylated human VEGF-A165 binding to recombinant human NRP1 receptor after 2 hrs by chemiluminescence analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50512570(CHEMBL4549611)
Affinity DataIC50:  7.76E+3nMAssay Description:Inhibition of biotinylated human VEGF-A165 binding to recombinant human NRP1 receptor after 2 hrs by chemiluminescence analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  8.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188996(5-chloro-3-(2-methoxyethylamino)-2-phenylindolizin...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313489((S)-2-{[3-(2-nitro-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  9.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188986(5-chloro-3-(phenethylamino)-2-o-tolylindolizine-1-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM94385((2-Allyloxy-3-ethoxy-benzyl)-(1H-[1,2,4]triazol-3-...)
Affinity DataIC50:  9.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188966(5-chloro-2-(2-mercaptophenyl)-3-(phenethylamino)in...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50189001(5-chloro-2-(4-(3-(dimethylamino)propoxy)phenyl)-3-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of recombinant human biotinylated VEGF-165A expressed in HEK293 cells binding to immobilized recombinant full length human FC-tagged NRP1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313493((S)-2-{[3-(1,2-Dimethyl-1H-imidazole-4-sulfonylami...)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188991(3-(3,4-dichlorobenzylamino)-5-chloro-2-phenylindol...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188993(5-chloro-2-(2-hydroxyethyl)-3-(phenethylamino)indo...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50188965(5-chloro-3-(phenethylamino)-2-(4-(trifluoromethoxy...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of VEGF165-NRP1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313484((S)-2-{[3-(4-Amino-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313485((S)-2-{[3-(3-Amino-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  1.40E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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