Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of ic50 for UniProtKB: Q8SPZ1
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity at monkey GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50291734(CHEMBL4159247)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50533863(CHEMBL4593521)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50533858(CHEMBL4449332)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50291733(CHEMBL4173065)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)
Affinity DataIC50:  4nMAssay Description:Binding affinity at monkey GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50291735(CHEMBL4169891)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50098391((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...)
Affinity DataIC50:  7nMAssay Description:Activity at rhesus monkey GnRH receptor by inositol phosphate functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50533858(CHEMBL4449332)
Affinity DataIC50:  13nMAssay Description:Antagonist activity against monkey GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Macaca mulatta)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50533863(CHEMBL4593521)
Affinity DataIC50:  32nMAssay Description:Antagonist activity against monkey GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed