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Found 6 of ic50 for UniProtKB: P21575
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318675(4-Chloro-2-{[2-(3-nitrophenyl)-1,3-dioxo-2,3-dihyd...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(CHEMBL1094197 | N,N'-(Propane-1,3-diyl)bis(6,7-dih...)
Affinity DataIC50:  4.04E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  9.95E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318674(4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318676(4-Chloro-2-{[2-(4-hydroxymethylphenyl)-1,3-dioxo-2...)
Affinity DataIC50:  6.90E+5nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed