Compile Data Set for Download or QSAR
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Found 4 of ic50 for UniProtKB: P55011
TargetSolute carrier family 12 member 2(Homo sapiens (Human))TBA
LigandPNGBDBM207990((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...)
Affinity DataIC50:  240nMAssay Description:Inhibition of NKCC1 in human HT-29 cells assessed as inhibition of rubidium uptake incubated for 20 min by atomic absorption spectroscopyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetSolute carrier family 12 member 2(Homo sapiens (Human))TBA
LigandPNGBDBM25903(3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid |...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of NKCC1 in human HT-29 cells assessed as inhibition of rubidium uptake incubated for 20 min by atomic absorption spectroscopyMore data for this Ligand-Target Pair
TargetSolute carrier family 12 member 2(Homo sapiens (Human))TBA
LigandPNGBDBM43891(N-(4-methyl-1,3-thiazol-2-yl)-2-(6-phenylpyridazin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at NKKC1 expressed in human HEK293 cells assessed as [86Rb] uptake after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 12 member 2(Homo sapiens (Human))TBA
LigandPNGBDBM50387285(CHEMBL2048846)
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at NKKC1 expressed in human HEK293 cells assessed as [86Rb] uptake after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed