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Found 200 of ic50 for UniProtKB: P48544
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347063(US10202390, Example 18)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347074(US10202390, Example 29)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50613996(CHEMBL5281961)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347062(US10202390, Example 17)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347061(3-(4-(isopropylamino)-5-(1-(tetrahydro-2H-pyran-4-...)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347058(US10202390, Example 13)
Affinity DataIC50:  3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347064(US10202390, Example 19)
Affinity DataIC50:  3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347072(3-(5-(1-(3-hydroxy-3-methylbutyl)-1H-pyrazol-4-yl)...)
Affinity DataIC50:  3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347067(US10202390, Example 22)
Affinity DataIC50:  4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347073(US10202390, Example 28)
Affinity DataIC50:  5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347070(US10202390, Example 25)
Affinity DataIC50:  5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347060(3-(4-(isopropylamino)-5-(4-propyl-1H-1,2,3-triazol...)
Affinity DataIC50:  6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585716(8-chloro-1-(2,6-dichlorophenyl)-5- ((2-(2-(2-(2- h...)
Affinity DataIC50:  6nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347056(2-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-N-isopro...)
Affinity DataIC50:  8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585717(8-chloro-1-(2,6-dichlorophenyl)-5- (2,3-dihydroxyp...)
Affinity DataIC50:  8nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347068(US10202390, Example 23)
Affinity DataIC50:  9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM585727(8-chloro-1-(2,6-dichlorophenyl)-5- (2-hydroxyethox...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347059(US10202390, Example 14)
Affinity DataIC50:  9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347057(US10202390, Example 12)
Affinity DataIC50:  9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585715(N-(2-((8-chloro-1-(2,6- dichlorophenyl)-2-methyl-4...)
Affinity DataIC50:  9nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585727(8-chloro-1-(2,6-dichlorophenyl)-5- (2-hydroxyethox...)
Affinity DataIC50:  9nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347071(US10202390, Example 26)
Affinity DataIC50:  10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585729(8-chloro-1-(2,6-dichlorophenyl)-2- methyl-5-(oxeta...)
Affinity DataIC50:  11nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50613997(CHEMBL5280047)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347065(US10202390, Example 20)
Affinity DataIC50:  12nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585719(8-chloro-1-(2,6-chlorophenyl)-5- (2,3-dihydroxy-3-...)
Affinity DataIC50:  13nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585741(US11530213, Example 62)
Affinity DataIC50:  13nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347048(US10202390, Example 3)
Affinity DataIC50:  14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347069(US10202390, Example 24)
Affinity DataIC50:  14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347066(US10202390, Example 21)
Affinity DataIC50:  14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585738(US11530213, Example 59)
Affinity DataIC50:  14nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585718((S)-8-chloro-1-(2,6- dichlorophenyl)-5-((2,3- dihy...)
Affinity DataIC50:  15nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585721(8-chloro-1-(2,6-dichlorophenyl)-5- (2-hydroxy-2-me...)
Affinity DataIC50:  15nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585742(US11530213, Example 63)
Affinity DataIC50:  16nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585737(US11530213, Example 58)
Affinity DataIC50:  17nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347051(US10202390, Example 6)
Affinity DataIC50:  18nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585764(US11530213, Example 85)
Affinity DataIC50:  19nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347055(US10202390, Example 10)
Affinity DataIC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585760(US11530213, Example 81)
Affinity DataIC50:  23nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585768(US11530213, Example 89)
Affinity DataIC50:  24nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585709(8-chloro-1-(2,6-dichlorophenyl)-5- (2-(2-(2-(2- hy...)
Affinity DataIC50:  25nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585694(5-(2,5,8,11,14,17- hexaoxanonadecan-19-yloxy)-8- c...)
Affinity DataIC50:  25nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM585709(8-chloro-1-(2,6-dichlorophenyl)-5- (2-(2-(2-(2- hy...)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585722(3,5-dichloro-4-(8-chloro-5- (((3R,4S)-4- hydroxyte...)
Affinity DataIC50:  26nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50613999(CHEMBL5289977)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585732(8-chloro-1-(2,6-dichlorophenyl)-5- (3-hydroxy-2- (...)
Affinity DataIC50:  28nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585720(8-chloro-1-(2,6-dichlorophenyl)-5- (3-hydroxy-2-(h...)
Affinity DataIC50:  28nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM347054(US10202390, Example 9)
Affinity DataIC50:  29nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585733(8-chloro-1-(2,6-dichlorophenyl)-5- (2,3-dihydroxyp...)
Affinity DataIC50:  29nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585705(8-chloro-1-(2,6-dichlorophenyl)-2- methyl-5-(2,3,4...)
Affinity DataIC50:  31nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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