Compile Data Set for Download or QSAR
Report error Found 12 of kd for UniProtKB: P36544
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKd:  1.06nMAssay Description:Dissociation constant for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50160557(5-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca-...)
Affinity DataKd:  1.06nMAssay Description:Dissociation constant for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50023331(4,13-Diaza-tricyclo[8.2.1.0*2,7*]trideca-2(7),3,5-...)
Affinity DataKd:  1.06nMAssay Description:Dissociation constant for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50023328(Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...)
Affinity DataKd:  1.06nMAssay Description:Dissociation constant for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKd:  1.06nMAssay Description:Dissociation constant for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKd:  6.30nMAssay Description:Displacement of [3H]epibatidine from chimeric human alpha7-5-HT3A receptor expressed in HEK293 cells after 2 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)
Affinity DataKd:  23nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50093255(2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxaz...)
Affinity DataKd:  92nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50061564(3-[1-(2,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-3,4,...)
Affinity DataKd:  158nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50248045((S)-1-(2-fluorophenyl)ethyl (S)-quinuclidin-3-ylca...)
Affinity DataKd:  200nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human recombinant alpha7 nAchRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50093253(3'-Methylspiro[1-azabicyclo[2.2.2]octane-3,5'-oxaz...)
Affinity DataKd:  220nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50093259(3'-Ethylspiro[1-azabicyclo[2.2.2]octane-3,5'-oxazo...)
Affinity DataKd:  690nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed