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TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to PARP3 (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240716(US9422243, 14)
Affinity DataKd:  10nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240720(US9422243, 20)
Affinity DataKd: <10nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240717(US9422243, 15)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240713(US9422243, 11)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240714(US9422243, 12)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240704(US9422243, 1)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240719(US9422243, 19)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240718(US9422243, 18)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib)
Affinity DataKd:  24nMAssay Description:Binding affinity to PARP3 (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240711(US9422243, 8)
Affinity DataKd:  30nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240715(US9422243, 13)
Affinity DataKd:  34nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167421(US9073893, 21)
Affinity DataKd:  40nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240721(US9422243, 21)
Affinity DataKd:  50nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167420(US9073893, 20)
Affinity DataKd:  50nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240712(US9422243, 10)
Affinity DataKd:  70nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataKd:  70nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240707(US9422243, 4)
Affinity DataKd:  90nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)
Affinity DataKd:  231nMAssay Description:Binding affinity to PARP3 (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataKd:  267nMAssay Description:Binding affinity to PARP3 (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167422(US9073893, 22)
Affinity DataKd:  270nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50226518(3-Aminobenzoesaeure | 3-aminobenzoic acid | CHEMBL...)
Affinity DataKd: >2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM124950(US8765972, 3)
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of fluorescent probe from human recombinant His/GST-tagged PARP3 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM124951(US8765972, 4)
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of fluorescent probe from human recombinant His/GST-tagged PARP3 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed