TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 catalytic domain (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0646nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein labeled LRRKtide peptide as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0759nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein labeled LRRKtide peptide as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.0800nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) preincubated with enzyme for 15 mins follo...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0813nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0813nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0813nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0813nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0832nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0880nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.0930nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.105nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.106nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.116nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: >0.158nMAssay Description:Inhibition of recombinant His6-Tev-LRRK2 (1326 to 2527 residues) (unknown origin) using LRRKtide as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.169nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein labeled LRRKtide peptide as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.174nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein labeled LRRKtide peptide as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.178nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.187nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein labeled LRRKtide peptide as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.197nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of N-terminal GST-fused human wild type LRRK2 using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.212nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.218nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.221nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.227nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.267nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.279nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST20-tagged human LRRK2 G2019S mutant using LRRKtide peptide preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST20-tagged LRRK2 in human SH-SY5Y cells assessed as reduction in pSer935 phosphorylation incubated for 90 mins by MSD assayMore data for this Ligand-Target Pair
Ligand Info
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human LRRK2 G2019S mutant expressed in human SH-SY5Y cells assessed as inhibition of tetracycline induced LRRK2 phosphorylation at Ser9...More data for this Ligand-Target Pair